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NIPER JEE 2018 Exam Pattern and Syllabus

National Institute of Pharmaceutical Education and Research conducts Joint Entrance examination (NIPER JEE 2018) for admission to doctoral and masters level courses in Pharmacy field. It is held on the national level. Courses like M. Pharm, M.S.(Pharm.), M.Tech.(Pharm.), MBA (Pharm.) and Ph.D. courses (Pharmaceutical and Biological Sciences disciplines) are open for admission through NIPER JEE.

  • The exam will be held in the offline mode (pen and paper mode).
  • Question paper will comprise questions which will be objective in nature and you need to select one out of the given 4 options.
  • The exam will throw 200 questions to be solved in 2 hours’ time.
  • Medium of NIPER JEE 2018 is English.
  • Each correct answer carries 1 mark and 0.25 negative marking will be deducted for every incorrectly answered question.
  • Chemistry, Biotechnology, Pharmacology, Pharmaceutical analysis are the core topics from which questions are asked.
  • You need to darken the circles in the ORS sheet using a HB pencil.

Online registration starts from fourth week of April 2018. NIPER JEE 2018 Application Form can be filled till second week of May 2018. The admit card will be available a week before the exam i.e. first week of June 2018. The exam will be held in second week of June 2018.

NIPER JEE 2018 Exam Pattern Highlights

Exam ModeOffline (Pen Paper Based)
Number of papers 1
Number of sections1
Question Paper Type MCQ
Total Marks200 marks
Exam duration 2 hours
Exam language English

NIPER JEE 2018 Exam Pattern in Detail

NIPER JEE exam pattern is as follows:

  • NIPER JEE contains 200 questions.
  • The exam is conducted in offline mode.
  • The time frame given to solve these questions is 2 hours.
  • Each correct answer carries 1 mark and 0.25 marks will be deducted for every incorrectly answered question.
  • Chemistry, Biotechnology, Pharmacology, Pharmaceutical analysis are the core topics from which questions are asked.
  • There will be a common paper for all Masters Programs including M.B.A (Pharm).  There is no approved syllabus set by NIPER for the entrance examination.
  • Subjects like Pharmacognosy or forensic pharmacy (Pharmaceutical Judispudence) are easier as compared to GPAT.
  • The syllabus is parallel to that of GATE entrance examination but the alteration is that, more significance is given for Chemistry linked subjects.
  • The applicants have to answer all the questions by blackening appropriate bubbles using HB pencil in the Objective Response Sheet (ORS).

NIPER JEE 2018 Marking Scheme

The marking scheme for NIPER JEE is very simple. The exam has 200 questions. Each carries 1 mark. Therefore, the maximum marks are 200. There is a negative mark of 25% of 1 that is 0.25or 1/4 for every incorrect answer marked in ORS sheet. And each correct answer will give you 1 mark.

NIPER JEE 2018 Syllabus

Natural ProductsSecondary metabolites
Methods of extraction, isolation and characterization of natural products
Biosynthetic pathways
Important therapeutic classes
Primary metabolites
Marine natural products
Plant growth regulators
Dietary antioxidants
StereochemistryPharmacology and toxicology
Evaluation of formulation, principles and methods of release control in oral formulations
Bioavailability, bioequivalence studies
Compartmental modeling
Dosage forms
Additives of formulation, types, examples, advantages, disadvantages, drug excipient interaction, incompatibility, various types of incompatibilities
Fischer, sawhorse and newmon projection formulas
Standardization of natural products
Various adrenergic, cholinergic and other receptors
Pharmaceutics and formulation (Pharmaceutical Technology)
Pharmacological effect, desired, undesired, toxic, adverse effects
Bioavailability, bioequivalence, various factors of ADME
Drug metabolism
Drug interactions, agonist, antagonist, protein binding, drug distribution, distribution volume, excretion pathways
Pharmacological screening
Mechanism of drug action
Drug-receptor interaction
Detailed study of CNS pharmacology Transdermal drug delivery systems
Chemotherapy and pathophysiology
Bioassay methods
Drug delivery systems (DDS)
Carriers in DDS
Biological sources of important classes of natural products
Drug targeting
Dosage form development- stages, implications of dosage form
Viscosity measurements
Pharmaceutical analysisStability testing of pharmaceuticals, various stability tests, kinetic studies, shelf life determination, thermal stability, formulation stability
Various analytical techniques
Tests: physical and chemical tests, limit tests, microbiological tests, biological tests, disintegration and dissolution tests.
Transdermal drug delivery systems (TDDS): principles, absorption enhancers, evaluation of TDDS.
Carriers in DDS: polymers and their classification, types, carbohydrates, surfactants, proteins, lipids, prodrugs etc. 
Drug delivery systems (DDS): NDDS models, osmotic pumps, various release patterns
Osmolality, osmolality, osmotic pressure, conductivity, Preservatives, Media for bioassay.
Spectroscopic methods
NMR Peaks
Particle sizing
Chromatography- detailed QA and QC: GLP, TQM, ISO system
Preformulation, cyclodextrin inclusion compounds
Crystallinity, polymorphism, solvates and hydrates, crystal habits, porosity, surface area flow properties.
Dosage forms, Stages of dosage form development
Biotechnology and biochemistryPharmaceutical technology
Classification of enzymes and their functions mechanism of action of
Genetic Engineering
Blotting techniques(Western, southern)
Gel electrophoresis
Gene cloning
Immunoassays, protein
RNA synthesis
DNA synthesis
rDNA technology
Gene expressionMutation
Transcription, translation
Recombination, bacteriophages
Methods, isolation of nucleic acids, enzymes in cloning
ChemistryBasic organic chemistry and biochemistry Stereochemistry
Osazone test
Medicinal chemistry and Bulk Drugs
Keto-enol tautomerism
IUPAC nomenclature
Introduction to thermal methods of analysis
Introduction to Redox reactions
Amino acids proteins
type of stereoisomer
Basic methods of synthesis of various organic compounds
Named reactions
Various Heterocycles, Heterocycle synthesis, reactions
Resolution methods
Reaction kinetics, first second third and pseudo first order reactions, radio labeling for determination of mechanism.
Racemic mixture
R and S nomenclature
Reactions like Cannizarro’s reaction
Pericyclic reactions
Ester hydrolysis
Huckel’s rule reaction mechanisms-
E and Z isomerism
Common condensation reactions like Aldol, Claisen Perkin, Dickmann, Darzen
Carbohydrates classification
AptitudeSimple Mathematics
logical reasoning and data analysis,
 questions based on English language 
PharmacologyBioavailability, bioequivalence, various factors of ADME
Bioassay methods, various requirements. Brief knowledge of the statistical tests.
Chemotherapy and pathophysiology- knowledge of antibiotics, their mode of action and the microorganisms responsible for various common diseases.
Diseases: study of the pharmacology of the diseases and drugs used with mode of action especially of diabetes, malaria, leishmaniasis, TB, hypertension, myocardial ischemia, inflammation, and immunomodualtion.
Study of basis of threshold areas of work in NIPER in pharmacology dept. Mentioned in brochure.
Detailed study of CNS pharmacology specially opiod receptors
Pharmacokinetics, pharmacodynamics, pharmacological effect, desired, undesired, toxic, adverse effects.
Drug metabolism: various pathways and other details.
Drug interactions, agonist, antagonist, Mechanism of drug action, drug-receptor interaction.
Various adrenergic, cholinergic and other receptors
partial agonist, protein binding, drug distribution, distribution volume, excretion pathways etc.
PhytochemistryMethods of extraction, isolation and characterization of natural products.
Various separation techniques used for isolation of natural products.
Biosynthetic pathways.
Primary metabolites, their examples
Secondary metabolites, various classes of secondary metabolites (eg. Alkaloids, glycosides, tannins, lignans, saponins, lipids, flavonoids, coumarins, etc.).
Important therapeutic classes: antidiabetics, hepatoprotectives, immmunomodulators, neutraceuticals, natural products for gynaecological disorders, anti-cancer, anti-viral (mainly anti-HIV), adaptogens etc.
Dietary antioxidants, Marine natural products, Plant growth regulators.
Fischer projection formulas.
Biological sources of important classes of natural products. (Selected ones only)
Standardization of natural products, analytical pharmacognosy.
What is difference between natural products and pharmacognosy ?
Some knowledge about types and preparation of ayurvedic formulatios like asava, arista etc.

NIPER JEE 2018 Recommended Books

Advanced Organic chemistryBahl and Bahlreactions, various methods of synthesis of organic compounds
Organic chemistryMorrison Boydreactions, various methods of synthesis of organic compounds
PharmacologyRang and Dale  -
BiochemistryU.Satyanarayana -
BiotechnologyU.Satyanarayana -
Elementary Organic SpectroscopyYR SharmaPrinciples and chemical applications
Medicinal chemistryWilliams and LemkePharmacy
 Mass SpectroscopySilversteinPharmaceutical analysis
Pharmaceutical BioassaysKastureBioassay and Screening
Analytical chemistryGarry Christen ()Chemical Methods

NIPER JEE 2018 Important Instructions

These are the following instructions you need to follow for NIPER JEE 2018

  • You should bring your own HB pencil
  • You should darken the circle properly in ORS sheet
  • Half or partially darkened circles will not be considered for evaluation
  • Write down your registration number clearly on the first sheet
  • No other stray marks should be made on the ORS sheets.
  • The duly filled application form needs to be sent to the institute.
  • Answers must be marked as per directions specified in the ORS sheet, question booklet and by the invigilators in the examination hall just before commencement of examination.
  • The circles need to be darkened only using black ball pen.




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